TianJin Keweijinhong

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TianJin Keweijinhong

Bactericidal alginate

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  • 洗必泰
  • 洗必泰

    It is a surface active fungicide, which has a strong antibacterial and bactericidal effect on gram-positive and negative-positive bacteria....


Performance and Use: 

Chlorhexidine chlorhexidine, also known as chlorhexidine, is a cationic surfactant, has a fairly strong broad-spectrum bacteriostatic, bactericidal and sterilizing effect, is a good bactericidal disinfectant, gram positive and negative bacteria antibacterial effect is stronger than benzalkonium bromide.Its positive charge, your mouth contain gargle adsorption on the surface of the plaques and the oral mucosa that with negatively charged, then the adsorption of drugs from these parts of dispersion, gradually have a lasting effect, precipitate until 24 hours after the concentration in saliva is reduced, the product of adsorption in bacterial cell size film permeation barrier, the cell contents leakage, low concentration when the bacteriostasis, high concentration antiseptic effect.Effective even in the presence of serum, blood, etc.It is not effective against spores, acid-fast bacilli, fungi and viruses.It is used for hand washing, hand soaking and skin disinfection of Chemicalbook in operation area.Oral cavity, throat infection, wound washing, instrument disinfection, room or operating room and other environmental disinfection.Cream or ointment for infantile eczema, small burns, scalds and pustules;Powder for prickly heat, eczema, dermatitis, erythema phase.Film is used for minor burns and scalds.Chlorhexidine is combined with hydrochloric acid, acetic acid and gluconic acid to form salts, respectively, chlorhexidine hydrochloride, chlorhexidine acetate and chlorhexidine gluconate.At present, chlorhexidine gluconate is commonly used in clinical practice in China, but chlorhexidine gluconate is mainly used in clinical practice in the United States and Europe. Especially in the recent 10 years, international research reports on chlorhexidine gluconate mainly focus on chlorhexidine gluconate.Chlorhexidine hydrochloride due to the low solubility in water, its preparation is mainly paste, coating agent, in the actual use has been basically eliminated.

Technical index:

Melting point:134-136°C(lit.)
Boiling point:641.45°C(roughestimate)
Refractive index:1.6300(estimate)
Storage condition:Storebelow+30°C.
Acidity coefficient (PKA):water:soluble0.08%at20°C
Acidity coefficient (PKA):pKa10.78(Uncertain)
Water solubility:0.08Chemicalbookg/100mL(20ºC)Merck:13,2108BRN:2826432
Chemical information:Chlorhexidine(55-56-1)

Method of application:

When applied, it can be prepared into aqueous solution or alcohol solution, and the purpose is achieved after a few minutes of contact with the solution.Aqueous solution (distilled water or deionized water) or alcohol solution concentration can be generally combined into 0.015% to 0.15%.Depending on the purpose of application, it can be prepared into other solutions or other dosage forms.

Packaging and storage:

【packaging】25kg/ drum, 5kg/ carton.
storage Seal save.

Safety and protection:

This product and soap, potassium iodide and other compatibility taboos.Use with borax, bicarbonate, carbonate, oxide, citrate, phosphate, and sulfate at a concentration of 0.05%.


Matters needing attention

Avoid contact with eyes.

In case of cork, the drug may lose its activity.

Cannot mix with soap, alkali, tincture of iodine, potassium permanganate, mercuric oxide or washing powder, because have antagonistic effect with anionic surfactant, unfavorable use as sterilization treatment disinfection.

It cannot be used for sterile treatment of surgical instruments.

Because it cannot kill hepatitis b virus, tuberculosis bacillus and spores, it cannot be used for the disinfection of excreta and secretions such as feces and sputum.

Avoid the use of Chemicalbook.

People who are allergic to this product, those with anterior tooth fillers (permanent pigmentation), and those with periodontitis (which can increase the calculus on the gums) are not allowed.Gargling is not recommended for patients aged 10 to 18

The needle and tube soaked with this product must be rinsed with clean water before spinal cord puncture.

1% chlorhexidine acetate aqueous solution is unstable, which precipitates out white precipitate after being placed. Generally, this acetate is used to prepare ointment, and gluconate can be used to prepare solution.

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